HIV-1, unlike other retroviruses such as MLV, is characterized by a complex genome that encodes two regulatory proteins (Tat and Rev) and four accessory proteins (Vif, Vpr, Vpu, and Nef) in addition to the common gag, pol, and env gene products.
Certain retroviruses, including HIV, insert their DNA in a non-random fraction of the host genome via poorly understood selection mechanisms. Here, we develop a biophysical model for retroviral
The koala retrovirus (KoRV) is a virus which, like other retroviruses such as HIV, inserts itself into the DNA of an infected cell. At some point in the past 50,000 years, KoRV has infected the
The cyclin-related genes recently discovered in the genome of a fish retrovirus may play a similar role. The clearest examples of viruses that can affect the cycling and differentiation state of the infected cells are those simple viruses that have acquired oncogenes from the cell. These viruses have been of great importance in the development
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is hiv a retrovirus